No agmatine-specific perioperative trial exists, but general supplement-discontinuation guidance applies directly given its blood pressure and blood sugar effects. A practical pre-op safety guide.
A 2020 open-label pilot study gave agmatine sulfate to small fiber neuropathy patients for two months and measured a 46% drop in pain. Here’s exactly what the trial did, who it studied, and why it isn’t proof yet.
Agmatine reduces tactile allodynia and lowers glucose in streptozotocin-diabetic rat studies. Here’s what the animal evidence actually shows, and why no diabetes-specific human trial exists yet.