Agmatine vs Taurine: One Has Meta-Analyses, One Has Mechanism
Taurine has 23 randomised trials and a small acute performance effect that the authors themselves rate as low certainty. Agmatine has none. What that asymmetry should mean for your stack.
Taurine has 23 randomised trials and a small acute performance effect that the authors themselves rate as low certainty. Agmatine has none. What that asymmetry should mean for your stack.
Agmatine sulfate is hygroscopic, so clumping is expected rather than a defect. Here is what clumping does and does not tell you, and how to store powder so it stays scoopable.
Acute stress raises brain agmatine nearly fourfold. Chronic stress depletes it. That apparent contradiction is the most useful thing in this literature, and no PTSD study exists.
Topical agmatine cut retinal ganglion cell loss from 55% to 19% in a rat glaucoma model. Why that doesn’t transfer to capsules, and the retracted paper still circulating as evidence.
A 2020 human study found ADHD children have elevated (not deficient) agmatine, likely compensatory. A 2021 rat study showed agmatine improved ADHD-relevant cognition. Neither supports agmatine as a human ADHD treatment.
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